What AOD-9604 Dosage Did Researchers Test?
Each amount belongs to a past study. None is a suggested amount for you.
What do these study amounts mean for you?
This page gives the AOD-9604 dosage used in studies of animals and people. These amounts are old study facts, not directions. AOD-9604 is not approved for human use, so you won't find a suggested dose or use guide here.
Human studies tested many pill amounts but found no clear weight loss. Other studies used shots to answer different questions. One pig study checked how quickly the compound left the blood. None of those choices created an approved dose.
Every amount below names the animal or person who received it and how researchers gave it. A rabbit knee shot and a pill taken by a person answer different questions. That keeps an old amount from sounding like advice for you.
Which pills and shots did past studies use?
Early work gave obese mice a pill form of the growth-hormone part numbered 177–191. That short part led to AOD-9604. In another mouse study, researchers gave belly shots during a 14-day test. Some mice lacked a working beta-3 switch that helps burn fat [1].
Early work in people used one vein shot ranging from 25 to 400 micrograms for each kilogram that the person weighed. Later studies in people used pills. Daily amounts ran from 0.25 mg through 54 mg. One 24-week study tested 0.25 mg, 0.5 mg, and 1 mg per day [5].
A rabbit knee study used 0.25 mg in each knee once a week. Some rabbits also received 6 mg of hyaluronic acid, a slippery substance found in joints. The study lasted 4–7 weeks [7]. It tested arthritic knees, not weight loss.
These amounts answer old study questions; they do not make a plan for human use. An AOD-9604 amount from a mouse or rabbit can't guide your care. Even the human amounts did not lead to clear weight loss.
Why did studies use both pills and shots?
A pig study found that whole AOD-9604 lasted about 3 minutes in blood after a vein shot. The body soon removed protein parts from one end [6]. That brief stay helped move the human weight-loss work toward pills. Animal work showed that the body could take in the pill [6].
The papers give little help on keeping the unused compound intact. A dry form with its water removed may last longer than it does in blood. Published studies don't give a tested home storage plan. Their pills and shots were chosen to answer set study questions.
Those forms don't create a use plan for you. A pig's vein shot and a rabbit's knee shot answered different questions. The human weight-loss work used tablets. None of these facts supplies an approved dose.
Did any tested pill amount lead to weight loss?
Changing the amount did not solve the weight-loss problem. About 900 adults with obesity joined roughly six trials. Daily pill amounts ran from 0.25 mg to 54 mg, and the trials lasted from 7 days to 24 weeks [5].
People taking AOD-9604 had much the same problems as people given placebo [5]. The main later trial showed no weight-loss edge for the drug. The company then closed its obesity work [14]. Testing a broad set of amounts did not show that the drug worked.
The numbers therefore remain old study facts, not a suggested amount for you. What happened in people matters more than any one dose. The list can't tell you what to take, and your doctor has no approved dose for the compound.